MacBreak
The only Macintosh show you'll ever need. Mac experts Leo Laporte, Kendra Arimoto, Emery Wells, Merlin Mann and Alex Lindsay talk about everything Mac, including hardware, software, pro apps, and tips. Every show includes interviews with the most interesting people in the Mac universe.
Although the show is no longer produced by Pixel Corps, you can enjoy the early episodes from the TWiT archives.